Maternal Serotonergic Antidepressant Use in Pregnancy and Risk of Seizures in Children

Kelsey Kathleen Wiggs, Ayehsa C. Sujan, Martin E. Rickert, Patrick D. Quinn, Henrik Larsson, Paul Lichtenstein, Brian M. D'Onofrio, A. Sara Oberg

https://doi.org/10.1212/WNL.0000000000200516

Randomized Phase 2 Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease

Florian P. Thomas, Thomas H. Brannagan, Russell J. Butterfield, Urvi Desai, Ali A. Habib, David N. Herrmann, Katy J. Eichinger, Nicholas E. Johnson, Chafic Karam, Alan Pestronk, Colin Quinn, Michael E. Shy, Jeffrey M. Statland, Sub H. Subramony, David Walk, Katherine Stevens-Favorite, Barry Miller, Ashley Leneus, Marcie Fowler, Marc van de Rijn, Kenneth M. Attie

https://doi.org/10.1212/WNL.0000000000200325

Association of Nonalcoholic Fatty Liver Disease and Fibrosis With Incident Dementia and Cognition: The Rotterdam Study

Tian Xiao, Laurens van Kleef, M. Kamran Ikram, Robert De Knegt, M. Arfan Ikram

https://doi.org/10.1212/WNL.0000000000200770

Phase 2 Trial of Rituximab in Acetylcholine Receptor Antibody-Positive Generalized Myasthenia Gravis: The BeatMG Study

Richard J. Nowak, Christopher S. Coffey, Jonathan M. Goldstein, Mazen M. Dimachkie, Michael Benatar, John T. Kissel, Gil I. Wolfe, Ted M. Burns, Miriam L. Freimer, Sharon Nations, Volkan Granit, A. Gordon Smith, David P. Richman, Emma Ciafaloni, Muhammad T. Al-Lozi, Laura Ann Sams, Dianna Quan, Eroboghene Ubogu, Brenda Pearson, Aditi Sharma, Jon W. Yankey, Liz Uribe, Michael Shy, Anthony A. Amato, Robin Conwit, Kevin C. O'Connor, David A. Hafler, Merit E. Cudkowicz, Richard J. Barohn, on behalf of the NeuroNEXT NN103 BeatMG Study Team

https://doi.org/10.1212/WNL.0000000000013121

Serum Neurofilament Light Association With Progression in Natalizumab-Treated Patients With Relapsing-Remitting Multiple Sclerosis

Claire Bridel, Cyra E. Leurs, Zoë Y.G.J. van Lierop, Zoé L.E. van Kempen, Iris Dekker, Harry A.M. Twaalfhoven, Bastiaan Moraal, Frederik Barkhof, Bernard M.J. Uitdehaag, Joep Killestein, Charlotte E. Teunissen

https://doi.org/10.1212/WNL.0000000000012752

Life Course of Physical Activity and Risk and Prognosis of Amyotrophic Lateral Sclerosis in a German ALS Registry

Angela Rosenbohm, Raphael Peter, Johannes Dorst, Jan Kassubek, Dietrich Rothenbacher, Gabriele Nagel, Albert C. Ludolph, on behalf of the ALS Registry Swabia Study Group

https://doi.org/10.1212/WNL.0000000000012829

Tumor Necrosis Factor Inhibition and Parkinson Disease: A Mendelian Randomization Study

Xiaoying Kang, Alexander Ploner, Nancy L. Pedersen, Sara Bandres-Ciga, Alastair J. Noyce, Karin Wirdefeldt, Dylan M. Williams

https://doi.org/10.1212/WNL.0000000000011630

Association of Group A Streptococcus Exposure and Exacerbations of Chronic Tic Disorders: A Multinational Prospective Cohort Study

Davide Martino, Anette Schrag, Zacharias Anastasiou, Alan Apter, Noa Benaroya-Milstein, Maura Buttiglione, Francesco Cardona, Roberta Creti, Androulla Efstratiou, Tammy Hedderly, Isobel Heyman, Chaim Huyser, Marcos Madruga, Pablo Mir, Astrid Morer, Nanette Mol Debes, Natalie Moll, Norbert Müller, Kirsten Müller-Vahl, Alexander Munchau, Peter Nagy, Kerstin Jessica Plessen, Cesare Porcelli, Renata Rizzo, Veit Roessner, Jaana Schnell, Markus Schwarz, Liselotte Skov, Tamar Steinberg, Zsanett Tarnok, Susanne Walitza, Andrea Dietrich, Pieter J. Hoekstra, ; on behalf of the EMTICS Collaborative Group

https://doi.org/10.1212/WNL.0000000000011610

Absence of GluD2 Antibodies in Patients With Opsoclonus-Myoclonus Syndrome

Mar Petit-Pedrol, Mar Guasp, Thais Armangue, Cinzia Lavarino, Andres Morales La Madrid, Albert Saiz, Francesc Graus, Josep Dalmau

https://doi.org/10.1212/WNL.0000000000011410

Estimated age of first exposure to American football and outcome from concussion

Jaclyn B. Caccese, Zac Houck, Thomas W. Kaminski, James R. Clugston, Grant L. Iverson, Kelsey N. Bryk, Jessie R. Oldham, Paul F. Pasquina, Steven P. Broglio, Thomas W. McAllister, Michael McCrea, April Marie (Reed) Hoy, Joseph B. Hazzard, Louise A. Kelly, Justus D. Ortega, Nicholas Port, Margot Putukian, T. Dianne Langford, Christopher C. Giza, Joshua T. Goldman, Holly J. Benjamin, Julianne D. Schmidt, Luis A. Feigenbaum, James T. Eckner, Jason P. Mihalik, Jessica Dysart Miles, Scott Anderson, Christina L. Master, Micky W. Collins, Anthony P. Kontos, Sara P.D. Chrisman, Alison Brooks, Jonathan C. Jackson, Gerald McGinty, Kenneth L. Cameron, Adam Susmarski, Patrick G. O'Donnell, Stefan Duma, Steve Rowson, Christopher M. Miles, Christopher T. Bullers, Brian H. Dykhuizen, Laura Lintner, Thomas A. Buckley, and the CARE Consortium Investigators

https://doi.org/10.1212/WNL.0000000000010672

Autoantibodies against the prion protein in individuals with PRNP mutations

Karl Frontzek, Manfredi Carta, Marco Losa, Mirka Epskamp, Georg Meisl, Alice Anane, Jean-Philippe Brandel, Ulrike Camenisch, Joaquín Castilla, Stéphane Haïk, Tuomas Knowles, Ewald Lindner, Andreas Lutterotti, Eric Vallabh Minikel, Ignazio Roiter, Jiri G. Safar, Raquel Sanchez-Valle, Dana Žáková, Simone Hornemann, Adriano Aguzzi, for the THAUTAN-MC Study Group

https://doi.org/10.1212/WNL.0000000000009183

Internet-based self-help randomized trial for motor functional neurologic disorder (SHIFT)

Jeannette M. Gelauff, Judith G.M. Rosmalen, Alan Carson, Joke M. Dijk, Martijn Ekkel, Glenn Nielsen, Jon Stone, Marina A.J. Tijssen

https://doi.org/10.1212/WNL.0000000000010381

Physical activity and risk of Alzheimer disease: A 2-sample mendelian randomization study

Sebastian E. Baumeister, André Karch, Martin Bahls, Alexander Teumer, Michael F. Leitzmann, Hansjörg Baurecht

https://doi.org/10.1212/WNL.0000000000010013

In vivo distribution of α-synuclein in multiple tissues and biofluids in Parkinson disease

Lana M. Chahine, Thomas G. Beach, Michael C. Brumm, Charles H. Adler, Christopher S. Coffey, Sherri Mosovsky, Chelsea Caspell-Garcia, Geidy E. Serrano, David G. Munoz, Charles L. White, John F. Crary, Danna Jennings, Peggy Taylor, Tatiana Foroud, Vanessa Arnedo, Catherine M. Kopil, Lindsey Riley, Kuldip D. Dave, Brit Mollenhauer, for the Systemic Synuclein Sampling Study

https://doi.org/10.1212/WNL.0000000000010404

Natalizumab in acute ischemic stroke (ACTION II): A randomized, placebo-controlled trial

Mitchell S.V. Elkind, Roland Veltkamp, Joan Montaner, S. Claiborne Johnston, Aneesh B. Singhal, Kyra Becker, Maarten G. Lansberg, Weihua Tang, Rachna Kasliwal, Jacob Elkins

https://doi.org/10.1212/WNL.0000000000010038

Antibodies against nodo-paranodal proteins are not present in genetic neuropathies

Lorena Martín-Aguilar, Elba Pascual-Goñi, Cinta Lleixà, Marina Frasquet, Herminia Argente, Angel Cano-Abascal, Jordi Diaz-Manera, Elena Cortés-Vicente, Ana Lara Pelayo-Negro, Teresa Sevilla, Ricard Rojas-García, Luis Querol

https://doi.org/10.1212/WNL.0000000000009189

Randomized placebo-controlled trial of the effects of aspirin on dementia and cognitive decline

Joanne Ryan, Elsdon Storey, Anne M. Murray, Robyn L. Woods, Rory Wolfe, Christopher M. Reid, Mark R. Nelson, Trevor T.J. Chong, Jeff D. Williamson, Stephanie A. Ward, Jessica E. Lockery, Suzanne G. Orchard, Ruth Trevaks, Brenda Kirpach, Anne B. Newman, Michael E. Ernst, John J. McNeil, Raj C. Shah, on behalf of the ASPREE Investigator Group

https://doi.org/10.1212/WNL.0000000000009277

Analysis of the association of MPO and MMP-9 with stroke severity and outcome: Cohort Study

Ilaria Maestrini, Madjid Tagzirt, Sophie Gautier, Annabelle Dupont, Anne-Marie Mendyk, Sophie Susen, Anne Tailleux, Emmanuelle Vallez, Bart Staels, Charlotte Cordonnier, Didier Leys, Regis Bordet

https://doi.org/10.1212/WNL.0000000000009179

Seasonal influenza vaccine and Guillain-Barré syndrome: A self-controlled case series study

Clémence Grave, Pauline Boucheron, Jérémie Rudant, Yann Mikaeloff, Pascale Tubert-Bitter, Sylvie Escolano, Mounia N. Hocine, Joël Coste, Alain Weill

https://doi.org/10.1212/WNL.0000000000009180

Randomized controlled trial of N-acetylcysteine therapy for RYR1-related myopathies

Joshua J. Todd, Tokunbor A. Lawal, Jessica W. Witherspoon, Irene C. Chrismer, Muslima S. Razaqyar, Monal Punjabi, Jeffrey S. Elliott, Fatoumata Tounkara, Anna Kuo, Monique O. Shelton, Carolyn Allen, Mary M. Cosgrove, Melody Linton, Darren Michael, Minal S. Jain, Melissa Waite, Bart Drinkard, Paul G. Wakim, James J. Dowling, Carsten G. Bönnemann, Magalie Emile-Backer, Katherine G. Meilleur

https://doi.org/10.1212/WNL.0000000000008872

Randomized trial of daily high-dose vitamin D3 in patients with RRMS receiving subcutaneous interferon β-1a

Raymond Hupperts, Joost Smolders, Reinhold Vieth, Trygve Holmøy, Kurt Marhardt, Myriam Schluep, Joep Killestein, Frederik Barkhof, Manolo Beelke, Luigi M.E. Grimaldi, on behalf of the SOLAR Study Group

https://doi.org/10.1212/WNL.0000000000008445

Early mobilization and quality of life after stroke: Findings from AVERT

Toby B. Cumming, Leonid Churilov, Janice Collier, Geoffrey Donnan, Fiona Ellery, Helen Dewey, Peter Langhorne, Richard I. Lindley, Marj Moodie, Amanda G. Thrift, Julie Bernhardt, on behalf of the AVERT Trial Collaboration group

https://doi.org/10.1212/WNL.0000000000007937

Repetitive TMS does not improve cognition in patients with TBI: A randomized double-blind trial

Iuri Santana Neville, Ana Luiza Zaninotto, Cintya Yukie Hayashi, Priscila Aparecida Rodrigues, Ricardo Galhardoni, Daniel Ciampi de Andrade, Andre Russowsky Brunoni, Robson L. Oliveira Amorim, Manoel Jacobsen Teixeira, Wellingson Silva Paiva

https://doi.org/10.1212/WNL.0000000000007748

A randomized controlled trial with everolimus for IQ and autism in tuberous sclerosis complex

Iris E. Overwater, André B. Rietman, Sabine E. Mous, Karen Bindels-de Heus, Dimitris Rizopoulos, Leontine W. ten Hoopen, Thijs van der Vaart, Floor E. Jansen, Ype Elgersma, Henriette A. Moll, Marie-Claire Y. de Wit

https://doi.org/10.1212/WNL.0000000000007749

INTREPAD: A randomized trial of naproxen to slow progress of presymptomatic Alzheimer disease

Pierre-François Meyer, Jennifer Tremblay-Mercier, Jeannie Leoutsakos, Cécile Madjar, Marie-Élyse Lafaille-Maignan, Melissa Savard, Pedro Rosa-Neto, Judes Poirier, Pierre Etienne, John Breitner, for the PREVENT-AD Research Group

https://doi.org/10.1212/WNL.0000000000007232

Prediagnostic plasma branched-chain amino acids and the risk of amyotrophic lateral sclerosis

Kjetil Bjornevik, Éilis J. O'Reilly, James D. Berry, Clary B. Clish, Sarah Jeanfavre, Ikuko Kato, Laurence N. Kolonel, Loic Le Marchand, Marjorie L. McCullough, Sabrina Paganoni, Michael A. Schwarzschild, Evelyn O. Talbott, Robert B. Wallace, Zhongli Zhang, JoAnn E. Manson, Alberto Ascherio

https://doi.org/10.1212/WNL.0000000000006669

Prediagnostic plasma metabolomics and the risk of amyotrophic lateral sclerosis

Kjetil Bjornevik, Zhongli Zhang, Éilis J. O'Reilly, James D. Berry, Clary B. Clish, Amy Deik, Sarah Jeanfavre, Ikuko Kato, Rachel S. Kelly, Laurence N. Kolonel, Liming Liang, Loic Le Marchand, Marjorie L. McCullough, Sabrina Paganoni, Kerry A. Pierce, Michael A. Schwarzschild, Aladdin H. Shadyab, Jean Wactawski-Wende, Dong D. Wang, Ying Wang, JoAnn E. Manson, Alberto Ascherio

https://doi.org/10.1212/WNL.0000000000007401

Clinical manifestations of homozygote allele carriers in Huntington disease

Esther Cubo, Saul-Indra Martinez-Horta, Frederic Sampedro Santalo, Asunción Martínez Descalls, Sara Calvo, Cecilia Gil-Polo, Ignacio Muñoz, Katia Llano, Natividad Mariscal, Dolores Diaz, Aranzazu Gutierrez, Laura Aguado, María A. Ramos-Arroyo, for the European HD Network

https://doi.org/10.1212/WNL.0000000000007147

A phase 3 randomized study evaluating sialic acid extended-release for GNE myopathy

Hanns Lochmüller, Anthony Behin, Yoseph Caraco, Heather Lau, Massimiliano Mirabella, Ivailo Tournev, Mark Tarnopolsky, Oksana Pogoryelova, Catherine Woods, Alexander Lai, Jinay Shah, Tony Koutsoukos, Alison Skrinar, Hank Mansbach, Emil Kakkis, Tahseen Mozaffar

https://doi.org/10.1212/WNL.0000000000006932

Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis

Kevin Messacar, Stefan Sillau, Sarah E. Hopkins, Catherine Otten, Molly Wilson-Murphy, Brian Wong, Jonathan D. Santoro, Andrew Treister, Harlori K. Bains, Alcy Torres, Luke Zabrocki, Julia R. Glanternik, Amanda L. Hurst, Jan A. Martin, Teri Schreiner, Naila Makhani, Roberta L. DeBiasi, Michael C. Kruer, Adriana H. Tremoulet, Keith Van Haren, Jay Desai, Leslie A. Benson, Mark P. Gorman, Mark J. Abzug, Kenneth L. Tyler, Samuel R. Dominguez

https://doi.org/10.1212/WNL.0000000000006670

Total intake of different minerals and the risk of multiple sclerosis

Marianna Cortese, Tanuja Chitnis, Alberto Ascherio, Kassandra L. Munger

https://doi.org/10.1212/WNL.0000000000006800

Statins do not increase risk of polyneuropathy

Janna K. Warendorf, Alexander F.J.E. Vrancken, Ruben P.A. van Eijk, Nora A. Visser, Leonard H. van den Berg, Nicolette C. Notermans

https://doi.org/10.1212/WNL.0000000000007148

Statins and perihemorrhagic edema in patients with spontaneous intracerebral hemorrhage

Jens Witsch, Fawaz Al-Mufti, E. Sander Connolly, Sachin Agarwal, Kara Melmed, David J. Roh, Jan Claassen, Soojin Park

https://doi.org/10.1212/WNL.0000000000006931

Haptoglobin genotype and aneurysmal subarachnoid hemorrhage: Individual patient data analysis

Ben Gaastra, Dianxu Ren, Sheila Alexander, Ellen R. Bennett, Dawn M. Bielawski, Spiros L. Blackburn, Mark K. Borsody, Sylvain Doré, James Galea, Patrick Garland, Tian He, Koji Iihara, Yoichiro Kawamura, Jenna L. Leclerc, James F. Meschia, Michael A. Pizzi, Rafael J. Tamargo, Wuyang Yang, Paul A. Nyquist, Diederik O. Bulters, Ian Galea

https://doi.org/10.1212/WNL.0000000000007397

Insular and anterior cingulate cortex deep stimulation for central neuropathic pain: Disassembling the percept of pain

Ricardo Galhardoni, Valquíria Aparecida da Silva, Luís García-Larrea, Camila Dale, Abrahão F. Baptista, Luciana Mendonça Barbosa, Luciana Mendes Bahia Menezes, Silvia R.D.T. de Siqueira, Fernanda Valério, Jefferson Rosi, Antonia Lilian de Lima Rodrigues, Diego Toledo Reis Mendes Fernandes, Priscila Mara Lorencini Selingardi, Marco Antônio Marcolin, Fábio Luís de Souza Duran, Carla Rachel Ono, Leandro Tavares Lucato, Ana Mércia B. L. Fernandes, Fábio E. F. da Silva, Lin T. Yeng, André R. Brunoni, Carlos A. Buchpiguel, Manoel J. Teixeira, Daniel Ciampi de Andrade

https://doi.org/10.1212/WNL.0000000000007396